

		Over 5 million people in the US and 25 million people worldwide suffer from heart failure.

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Our Solution - Innovative Devices for the Treatment of Diastolic Heart Failure

CorAssist is developing a pipeline of elastic, self-expanding devices that are attached to the left ventricle, either externally or internally. The devices operate by transferring energy harnessed during systole (contraction) to the left ventricle during diastole (relaxation) to improve diastolic performance. CorAssist’s devices deal with the core problems of diastolic heart failure – the stiffening of the myocardial tissue and impaired relaxation – by directly enhancing the elastic characteristics of the left ventricular wall.

ImCardia™

The ImCardia™ is an elastic self-expanding device that is attached to the external left ventricle surface of the heart through a simple off-pump procedure. It applies an outward expansion force on the ventricular wall to improve diastolic dynamic and filling performance.
Click here to see the ImCardia™ demo.
In-vivo Safety evaluation on healthy model demonstrated that the device is safe at 6 month follow up (including: systolic performance, general clinical evaluation and extreme conditions tests).
In-vivo Efficacy evaluation on diseased animal model with hypertrophic left ventricles revealed diastolic properties improvement.

Ongoing results from Clinical safety study in which the ImCardia is implanted in patients admitted for Aortic valve replacement due to Aortic stenosis and suffering from Diastolic Dysfunction reviled safety profile with first patients reaching 1 year follow-up.
Efficacy clinical study on DHF patient is about to start recruitment during 2009.

ImCardia™ MIS

The ImCardia™ MIS is a second generation, minimally invasive version of the ImCardia™ device. It will allow for smaller incisions, less patient trauma and faster recovery times.

CORolla™

The CORolla™ is an elastic device implanted inside the left ventricle in a minimally invasive or percutaneous procedure. The device applies direct internal expansion forces distributed on the left ventricle wall and the septum to improve diastolic function.
Click here to see the CORolla™ demo.